Plasticity of intrinsic neuronal excitability
نویسندگان
چکیده
منابع مشابه
Psychostimulant-induced plasticity of intrinsic neuronal excitability in ventral subiculum.
Psychostimulant drugs such as amphetamine are prescribed to increase vigilance, suppress appetite, and treat attention disorders, but they powerfully activate the dopamine system and have serious abuse potential. Repeated psychostimulant exposure induces neuronal plasticity within the mesolimbic dopamine system. Here we present evidence that repeated amphetamine exposure results in a suppressio...
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Long-lasting plasticity of synaptic transmission is classically thought to be the cellular substrate for information storage in the brain. Recent data indicate however that it is not the whole story and persistent changes in the intrinsic neuronal excitability have been shown to occur in parallel to the induction of long-term synaptic modifications. This form of plasticity depends on the regula...
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Long-term memory is supported not only by modulation of synaptic strength, but also by modifications in intrinsic neuronal properties. Learning-induced enhancement of neuronal excitability has been shown in the hippocampus and the piriform cortex, where it lasts for days and is involved in maintaining the learned skills. The basolateral amygdala (BLA) is suggested to encode positive and negativ...
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The nervous system faces an extremely difficult task. It must be flexible, both during development and in adult life, so that it can respond to a variety of environmental demands and produce adaptive behavior. At the same time the nervous system must be stable, so that the neural circuits that produce behavior function throughout the lifetime of the animal and that changes produced by learning ...
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ژورنال
عنوان ژورنال: Current Opinion in Neurobiology
سال: 2019
ISSN: 0959-4388
DOI: 10.1016/j.conb.2018.09.001